Shiseido Skin Care Products

 

 

Anti-Aging Research

Shiseido collaborates closely with many external organizations in its advanced research on skin aging. We know that the basement membrane connecting the epidermis and the dermis helps to maintain the functions of the skin. But ultraviolet rays accelerate enzyme production in the epidermis, destroying the basement membrane, secondarily causing abnormalities in epidermal turnover and in the dermal structure. Shiseido identified this as the cause of early aging and of accelerating facial wrinkle formation. We developed compounds to suppress enzyme breakdown and restore the basement membrane. Many of our products contain these compounds.
It has been established that ultraviolet rays promote angiogenesis ( i.e.the formation of blood vessels ) in the dermis. These blood vessels are conduits for inflammatory cells that damage the structure of the dermis, leading to wrinkle formation. We then focused our attention on a compound that inhibits endogenous angiogenesis and are anticipating its development into a new anti-wrinkle treatment.